The Role of PARP Inhibitors in the Treatment of Ovarian Carcinomas.
19 mai 2012
Tinker AV, Gelmon K
Curr Pharm Des

Numb regulates stability and localization of the mitotic kinase PLK1 and is required for transit through mitosis.
19 mai 2012
Schmit TL, Nihal M, Ndiaye MA, Setaluri V, Spiegelman VS, Ahmad N
Cancer Res

Tissue-based predictors of germ-line BRCA1 mutations: implications for triaging of genetic testing.
19 mai 2012
de la Cruz J, Andre F, Harrell RK, Bassett RL, Arun B, Mathieu MC, Delaloge S, Gilcrease MZ
Hum Pathol

Comprehensive chromosome screening and embryo selection: moving toward single euploid blastocyst transfer.
16 mai 2012
Forman EJ, Hong KH, Treff NR, Scott RT
Semin Reprod Med

Is the Addition of the Ductus Venosus Useful when Screening for Aneuploidy and Congenital Heart Disease in Fetuses with Normal Nuchal Translucency?
16 mai 2012
Prats P, Ferrer Q, Comas C, Rodríguez I
Fetal Diagn Ther

Investigation on BRCA1 SNPs and its effects on mastitis in Chinese commercial cattle.
16 mai 2012
Yuan ZR, Li JY, Li J, Gao X, Gao HJ, Xu SZ
Gene

P190B RhoGAP Regulates Chromosome Segregation in Cancer Cells.
15 mai 2012
Hwang M, Peddibhotla S, McHenry P, Chang P, Yochum Z, Park KU, Sears JC, Vargo-Gogola T
Cancers (Basel)

Genomic Characterisation of Acral Melanoma Cell Lines.
15 mai 2012
Furney SJ, Turajlic S, Fenwick K, Lambros MB, Mackay A, Ricken G, Mitsopoulos C, Kozarewa I, Hakas J, Zvelebil M, Lord CJ, Ashworth A, Reis-Filho JS, Herlyn M, Murata H, Marais R
Pigment Cell Melanoma Res

The validation of a 15 STR multiplex PCR for Cannabis species.
12 mai 2012
Köhnemann S, Nedele J, Schwotzer D, Morzfeld J, Pfeiffer H
Int J Legal Med

Molecular cytogenetic and genetic aspects of globozoospermia: a review.
12 mai 2012
Perrin A, Coat C, Nguyen MH, Talagas M, Morel F, Amice J, De Braekeleer M
Andrologia

BRCA, the Oviduct, and the Space and Time Continuum of Pelvic Serous Carcinogenesis.
12 mai 2012
Crum CP, McKeon FD, Xian W
Int J Gynecol Cancer

DNA-testing for BRCA1/2 prior to genetic counseling in patients with breast cancer: Design of an intervention study, DNA-direct.
10 mai 2012
Sie AS, Spruijt L, van Zelst-Stams WA, Mensenkamp AR, Ligtenberg MJ, Brunner HG, Prins JB, Hoogerbrugge N
BMC Womens Health

Association of EGFR mutation or ALK rearrangement with expression of DNA repair and synthesis genes in never-smoker women with pulmonary adenocarcinoma.
10 mai 2012
Ren S, Chen X, Kuang P, Zheng L, Su C, Li J, Li B, Wang Y, Liu L, Hu Q, Zhang J, Tang L, Li X, Zhou C, Schmid-Bindert G
Cancer

Improved diagnostic accuracy by using secondary ultrasound markers in the first-trimester screening for trisomies 21, 18 and 13 and Turner syndrome.
10 mai 2012
Karadzov-Orlic N, Egic A, Milovanovic Z, Marinkovic M, Damnjanovic-Pazin B, Lukic R, Joksic I, Curkovic A, Mikovic Z
Prenat Diagn

Progressive telomere dysfunction causes cytokinesis failure and leads to the accumulation of polyploid cells.
10 mai 2012
Pampalona J, Frías C, Genescà A, Tusell L
PLoS Genet

Frequency of sex chromosomal disomy in spermatozoa of normal and oligozoospermic Iranian patients and its effects on fertilisation and implantation rates after ICSI.
9 mai 2012
Ghoraeian P, Mozdarani H, Aleyasin A, Alizadeh-Nili H
Andrologia

The 58-kDa microspherule protein (MSP58) is a novel brahma-related gene 1 (BRG1)-associated protein that modulates the p53-p21 senescence pathway.
9 mai 2012
Hsu CC, Lee YC, Yeh SH, Chen CH, Wu CC, Wang TY, Chen YN, Hung LY, Liu YW, Chen HK, Hsiao YT, Wang WS, Tsou JH, Tsou YH, Wu MH, Chang WC, Lin DY
J Biol Chem

Detection of Microdeletion 22q11.2 in a Fetus by Next-Generation Sequencing of Maternal Plasma.
9 mai 2012
Jensen TJ, Dzakula Z, Deciu C, van den Boom D, Ehrich M
Clin Chem

Age-related aneuploidy through cohesion exhaustion. 'Exploring aneuploidy: the significance of chromosomal imbalance' review series.
9 mai 2012
Jessberger R
EMBO Rep

Losing balance: the origin and impact of aneuploidy in cancer. 'Exploring aneuploidy: the significance of chromosomal imbalance' review series.
9 mai 2012
Holland AJ, Cleveland DW
EMBO Rep

Multiple genotoxic activities of ptaquiloside in human lymphocytes: Aneugenesis, clastogenesis and induction of sister chromatid exchange.
9 mai 2012
Gil da Costa RM, Coelho P, Sousa R, Bastos MM, Porto B, Teixeira JP, Malheiro I, Lopes C
Mutat Res

Interest and attitudes of patients, cancer physicians, medical students and cancer researchers towards a spectrum of genetic tests relevant to breast cancer patients.
9 mai 2012
Ngoi N, Lee SC, Hartman M, Khin LW, Wong A
Breast

Detectable clonal mosaicism and its relationship to aging and cancer.
9 mai 2012
Jacobs KB, Yeager M, Zhou W, Wacholder S, Wang Z, Rodriguez-Santiago B, Hutchinson A, Deng X, Liu C, Horner MJ, Cullen M, Epstein CG, Burdett L, Dean MC, Chatterjee N, Sampson J, Chung CC, Kovaks J, Gapstur SM, Stevens VL, Teras LT, Gaudet MM, Albanes D, Weinstein SJ, Virtamo J, Taylor PR, Freedman ND, Abnet CC, Goldstein AM, Hu N, Yu K, Yuan JM, Liao L, Ding T, Qiao YL, Gao YT, Koh WP, Xiang YB, Tang ZZ, Fan JH, Aldrich MC, Amos C, Blot WJ, Bock CH, Gillanders EM, Harris CC, Haiman CA, Henderson BE, Kolonel LN, Le Marchand L, McNeill LH, Rybicki BA, Schwartz AG, Signorello LB, Spitz MR, Wiencke JK, Wrensch M, Wu X, Zanetti KA, Ziegler RG, Figueroa JD, Garcia-Closas M, Malats N, Marenne G, Prokunina-Olsson L, Baris D, Schwenn M, Johnson A, Landi MT, Goldin L, Consonni D, Bertazzi PA, Rotunno M, Rajaraman P, Andersson U, Freeman LE, Berg CD, Buring JE, Butler MA, Carreon T, Feychting M, Ahlbom A, Gaziano JM, Giles GG, Hallmans G, Hankinson SE, Hartge P, Henriksson R, Inskip PD, Johansen C, Landgren A, McKean-Cowdin R, Michaud DS, Melin BS, Peters U, Ruder AM, Sesso HD, Severi G, Shu XO, Visvanathan K, White E, Wolk A, Zeleniuch-Jacquotte A, Zheng W, Silverman DT, Kogevinas M, Gonzalez JR, Villa O, Li D, Duell EJ, Risch HA, Olson SH, Kooperberg C, Wolpin BM, Jiao L, Hassan M, Wheeler W, Arslan AA, Bueno-de-Mesquita HB, Fuchs CS, Gallinger S, Gross MD, Holly EA, Klein AP, Lacroix A, Mandelson MT, Petersen G, Boutron-Ruault MC, Bracci PM, Canzian F, Chang K, Cotterchio M, Giovannucci EL, Goggins M, Bolton JA, Jenab M, Khaw KT, Krogh V, Kurtz RC, McWilliams RR, Mendelsohn JB, Rabe KG, Riboli E, Tjønneland A, Tobias GS, Trichopoulos D, Elena JW, Yu H, Amundadottir L, Stolzenberg-Solomon RZ, Kraft P, Schumacher F, Stram D, Savage SA, Mirabello L, Andrulis IL, Wunder JS, García AP, Sierrasesúmaga L, Barkauskas DA, Gorlick RG, Purdue M, Chow WH, Moore LE, Schwartz KL, Davis FG, Hsing AW, Berndt SI, Black A, Wentzensen N, Brinton LA, Lissowska J, Peplonska B, McGlynn KA, Cook MB, Graubard BI, Kratz CP, Greene MH, Erickson RL, Hunter DJ, Thomas G, Hoover RN, Real FX, Fraumeni JF, Caporaso NE, Tucker M, Rothman N, Pérez-Jurado LA, Chanock SJ
Nat Genet

Roles of 14-3-3η in mitotic progression and its potential use as a therapeutic target for cancers.
9 mai 2012
Lee CG, Park GY, Han YK, Lee JH, Chun SH, Park HY, Lim KH, Kim EG, Choi YJ, Yang K, Lee CW
Oncogene

Computational investigation of pathogenic nsSNPs in CEP63 protein.
5 mai 2012
Kumar A, Purohit R
Gene

'Cancer doesn't have an age': Genetic testing and cancer risk management in BRCA1/2 mutation-positive women aged 18-24.
3 mai 2012
Werner-Lin A, Hoskins LM, Doyle MH, Greene MH
Health (London)

A Dual Role for UVRAG in Maintaining Chromosomal Stability Independent of Autophagy.
1er mai 2012
Zhao Z, Oh S, Li D, Ni D, Pirooz SD, Lee JH, Yang S, Lee JY, Ghozalli I, Costanzo V, Stark JM, Liang C
Dev Cell

Breast cancer genetic counseling after diagnosis but before treatment: A pilot study on treatment consequences and psychological impact.
1er mai 2012
Wevers MR, Hahn DE, Verhoef S, Bolhaar MD, Ausems MG, Aaronson NK, Bleiker EM
Patient Educ Couns

Reduction in sperm aneuploidy levels in severe oligoasthenoteratospermic patients after medical therapy: a preliminary report.
1er mai 2012
Cavallini G, Cristina Magli M, Crippa A, Pia Ferraretti A, Gianaroli L
Asian J Androl

Tracking fetal development through molecular analysis of maternal biofluids.
1er mai 2012
Edlow AG, Bianchi DW
Biochim Biophys Acta

Relationship between columnar cell changes and low-grade carcinoma in situ of the breast-a cytogenetic study.
1er mai 2012
Go EM, Tsang JY, Ni YB, Yu AM, Mendoza P, Chan SK, Lam CC, Lui PC, Tan PH, Tse GM
Hum Pathol

Meiotic segregation study of a novel t(3;6)(q21;q23) in an infertile man using fluorescence in situ hybridization (FISH).
1er mai 2012
Mokánszki A, Ujfalusi A, Balogh E, Sümegi A, Antal-Szalmás P, Bazsáné ZK, Molnár Z, Varga A, Sápy T, Jakab A, Oláh E
Syst Biol Reprod Med

Clinical significance of large rearrangements in BRCA1 and BRCA2.
1er mai 2012
Judkins T, Rosenthal E, Arnell C, Burbidge LA, Geary W, Barrus T, Schoenberger J, Trost J, Wenstrup RJ, Roa BB
Cancer

Digital PCR for Noninvasive Detection of Aneuploidy: Power Analysis Equations for Feasibility.
28 avril 2012
Evans MI, Wright DA, Pergament E, Cuckle HS, Nicolaides KH
Fetal Diagn Ther

A potential probe set of fluorescence in situ hybridization for detection of lung cancer in bronchial brushing specimens.
28 avril 2012
Liu YZ, Wang Z, Fang LL, Li L, Cao J, Xu X, Han YL, Cai Y, Wang LX, Wang MR
J Cancer Res Clin Oncol

Sperm DNA fragmentation index does not correlate with the sperm or embryo aneuploidy rate in recurrent miscarriage or implantation failure patients.
28 avril 2012
Bronet F, Martínez E, Gaytán M, Liñán A, Cernuda D, Ariza M, Nogales M, Pacheco A, San Celestino M, Garcia-Velasco JA
Hum Reprod

Exploring the relationship between the severity of oligozoospermia and the frequencies of sperm chromosome aneuploidies.
28 avril 2012
Durak Aras B, Aras I, Can C, Toprak C, Dikoglu E, Bademci G, Ozdemir M, Cilingir O, Artan S
Andrologia

Pro-oxidant Induced DNA Damage in Human Lymphoblastoid Cells: Homeostatic Mechanisms of Genotoxic Tolerance.
28 avril 2012
Seager A, Shah UK, Mikhail J, Nelson B, Marquis B, Doak S, Johnson G, Griffiths S, Carmichael P, Scott S, Scott A, Jenkins G
Toxicol Sci

Complex Trait Analysis of Ventricular Septal Defects Caused by Nkx2-5 Mutation.
28 avril 2012
Winston JB, Schulkey CE, Chen IB, Regmi SD, Efimova M, Erlich JM, Green CA, Aluko A, Jay PY
Circ Cardiovasc Genet

Double heterozygosity for mutations in BRCA1 and BRCA2 in German breast cancer patients: implications on test strategies and clinical management.
28 avril 2012
Heidemann S, Fischer C, Engel C, Fischer B, Harder L, Schlegelberger B, Niederacher D, Goecke TO, Doelken SC, Dikow N, Jonat W, Morlot S, Schmutzler RC, Arnold NK
Breast Cancer Res Treat

Aggressiveness of human melanoma xenograft models is promoted by aneuploidy-driven gene expression deregulation.
28 avril 2012
Mathieu V, Pirker C, Schmidt WM, Spiegl-Kreinecker S, Lötsch D, Heffeter P, Hegedus B, Grusch M, Kiss R, Berger W
Oncotarget

Sperm meiotic segregation, aneuploidy and high risk of delivering an affected offspring in carriers of non-Robertsonian translocation t(13;15).
26 avril 2012
Kasikova K, Vozdova M, Prinosilova P, Gaillyova R, Hanakova M, Rubes J
J Assist Reprod Genet

Cell Cycle Activation and Aneuploid Neurons in Alzheimer's Disease.
26 avril 2012
Arendt T
Mol Neurobiol

Directed therapy for patients with myelodysplastic syndromes (MDS) by suppression of cyclin D1 with ON 01910.Na.
26 avril 2012
Olnes MJ, Shenoy A, Weinstein B, Pfannes L, Loeliger K, Tucker Z, Tian X, Kwak M, Wilhelm F, Yong AS, Maric I, Maniar M, Scheinberg P, Groopman J, Young NS, Sloand EM
Leuk Res

Genomic differences in benign and malignant follicular thyroid tumours using 1-Mb array-comparative genomic hybridisation.
26 avril 2012
Qureshi AA, Collins VP, Jani P
Eur Arch Otorhinolaryngol

Collective evidence supports neutrality of BRCA1 V1687I, a novel sequence variant in the conserved THV motif of the first BRCT repeat.
26 avril 2012
Cortesi L, De Nicolo A, Medici V, Marino M, Turchetti D, Pradella LM, Rossi G, Parisini E, Federico M
Breast Cancer Res Treat

PTTG in Thyroid Cancer.
25 avril 2012
Lewy GD, Sharma N, Seed RI, Smith VE, Boelaert K, McCabe CJ
J Endocrinol Invest

Chromosomal abnormalities in embryos from couples with a previous aneuploid miscarriage.
25 avril 2012
Al-Asmar N, Peinado V, Vera M, Remohí J, Pellicer A, Simón C, Hassold T, Rubio C
Fertil Steril

The role of BRCA1 and BRCA2 in prostate cancer.
25 avril 2012
Castro E, Eeles R
Asian J Androl

Does 45,X/46,XX mosaicism with 6-28% of aneuploidy affect the outcomes of IVF or ICSI?
22 avril 2012
Homer L, Morel F, Gallon F, Le Martelot MT, Amice V, Kerlan V, De Braekeleer M
Eur J Obstet Gynecol Reprod Biol

Spindle assembly checkpoint signalling is uncoupled from chromosomal position in mouse oocytes.
22 avril 2012
Gui L, Homer H
Development

Cytogenetic analysis of 531 Chinese women with premature ovarian failure.
22 avril 2012
Jiao X, Qin C, Li J, Qin Y, Gao X, Zhang B, Zhen X, Feng Y, Simpson JL, Chen ZJ
Hum Reprod